Best OTC Sleep Aids for Travel

Traveling can be exciting, but getting a good night's sleep while on the move? Not so much. Whether it’s noisy flights, unfamiliar hotel beds, or jet lag, sleep disruptions are common. Luckily, over-the-counter (OTC) sleep aids can help you rest and recharge no matter where you are. In this guide, we’ll cover the best OTC options that are safe, effective, and convenient for your next trip.

Important Notice: Please consult a doctor if you have any medical conditions. We do not provide medical advice or make claims, and we are not liable for individual health outcome

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Key Highlights

  • Founded by three former Bose engineers with extensive experience in audio tech
  • Sleepbuds® actively mask unwanted sounds like snoring, traffic, and environmental noises with calming, science-backed audio.
  • Ultra-soft silicone tips designed to support every sleeping position, ensuring a secure and comfortable fit.
  • Up to 10 hours of continuous use with extra charges from the Smart Case.
  • Built-in biometric and environmental sensors offering personalized sleep reports
  • Personal alarm gently wakes you without disturbing your partner

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    1. WELMATE Nighttime Sleep Aid

    WELMATE offers a nighttime sleep aid containing 25 mg of Doxylamine Succinate, intended for occasional sleeplessness support. This over-the-counter product is intended for both home use and travel, assisting users in falling asleep faster and staying asleep longer. It is comparable to similar OTC sleep aids and is made without pain relievers. Each bottle contains 200 tablets, offering a long-term solution for those experiencing sleep disruptions.

    WELMATE's sleep aid is designed for adults and children over the age of 12, and it can be especially useful for those dealing with stress-related sleep issues or time zone changes during travel. The product aims to reduce morning grogginess and promote a sense of restfulness.

    Key Highlights:

    • Contains 25 mg Doxylamine Succinate per tablet
    • Non-habit forming and safe for long-term use
    • Clinically tested and proven effective for sleeplessness relief
    • Available in a 200-tablet bottle for extended use
    • No next-day grogginess

    Who it’s best for:

    • Adults and children over 12
    • People experiencing stress-related sleep issues
    • Travelers dealing with jet lag or time zone changes
    • Individuals looking for a non-habit-forming sleep aid

    2. Kalms Night

    Kalms Night is a natural herbal remedy designed to help adults improve their sleep quality. It primarily contains valerian root extract, traditionally associated with relaxation. Kalms comes in tablet form, and each pack contains 50 tablets. The product is intended for short-term use to support restful, natural sleep without the side effects commonly associated with stronger medications. It is not recommended for individuals under the age of 18 and is intended for adult users looking for a gentle sleep aid.

    It is easy to administer, with users instructed to take four tablets 30-60 minutes before bedtime. While some users report positive effects, others may experience varying results. The product should not be used with other sleep medications, and it is advised to consult a healthcare provider if symptoms persist.

    Key Highlights:

    • Contains valerian root extract, a traditional remedy for sleep and stress
    • Pack of 50 tablets designed for short-term use
    • For adult users; not recommended for individuals under 18
    • Instructions: take 4 tablets 30-60 minutes before sleep
    • Not for use during pregnancy or breastfeeding
    • Designed to support refreshing natural sleep without next-day drowsiness

    Who it’s best for:

    • Adults looking for a mild, natural sleep aid
    • People experiencing mild sleep issues due to stress or anxiety
    • Travelers or individuals needing a temporary solution for sleep disturbances

    3. Kirkland Signature Sleep Aid Doxylamine Succinate 25 Mg

    The Kirkland Signature Sleep Aid contains 25 mg of Doxylamine Succinate, designed to support sleep for adults who struggle with falling asleep. It comes in a tablet form, packaged in a 96-count bottle. This product is often compared to other sleep aids containing similar active ingredients, such as Unisom Sleep Tabs. It is marketed as a nighttime sleep aid and is available without a prescription.

    This sleep aid is often used by individuals who experience occasional sleeplessness, helping them fall asleep faster with just one tablet per dose. While it supports sleep effectively, some users report feeling groggy the following morning if not enough time is allowed for the effects to wear off. Like many over-the-counter sleep aids, it is intended for short-term use and should be taken as directed.

    Key Highlights:

    • Contains 25 mg of Doxylamine Succinate
    • Packaged in a 96-count bottle
    • Non-habit-forming
    • Compares to Unisom Sleep Tabs
    • Recommended for nighttime use

    Who it’s best for:

    • Adults with occasional sleeplessness
    • Those who prefer a non-prescription sleep aid
    • Individuals looking for an affordable sleep support option

    4. Benadryl Ultratabs Antihistamine Allergy Relief Medicine

    Benadryl Ultratabs are designed to provide relief from allergy and cold symptoms, including sneezing, runny nose, and itchy eyes or throat. These tablets contain 25 mg of diphenhydramine HCl, which is an antihistamine that helps manage hay fever and upper respiratory allergies. This over-the-counter medicine is suitable for adults and children over six years old, offering temporary relief from common allergens like pollen, dust, mold, and pet dander. It also addresses symptoms of the common cold, such as runny nose and sneezing.

    The product is available in a 100-count package and comes in an easy-to-swallow, small, coated tablet form. While primarily formulated for allergy relief, diphenhydramine also causes drowsiness, making it an option for those looking to sleep better while traveling. However, users should be cautious, as marked drowsiness may occur, and it is recommended to avoid alcohol or sedatives when using this product.

    Key Highlights:

    • Contains 25 mg of diphenhydramine HCl per tablet
    • Intended for relief from common allergy symptoms such as sneezing and itchy eyes
    • Temporarily relieves cold symptoms like a runny nose and sneezing
    • Suitable for adults and children ages 6+
    • Available in a 100-count package with easy-to-swallow tablets

    Who it’s best for:

    • Travelers needing both allergy relief and assistance with sleep during trips
    • Adults and children ages 6+ dealing with upper respiratory allergies
    • People experiencing seasonal allergies from pollen, dust, and pet dander
    • Individuals looking for multi-symptom cold and allergy relief

    5. Natrol 10 mg Melatonin Gummies

    Natrol 10 mg Melatonin Gummies are designed to provide sleep support for adults experiencing occasional sleeplessness. These strawberry-flavored gummies contain 10 mg of melatonin per serving and are free from artificial flavors, synthetic dyes, and other common allergens. They are also vegetarian and non-GMO, made from clean ingredients, including coconut oil, offering an easy-to-take alternative to traditional tablets. The gummies are formulated to support natural sleep patterns while traveling or under stress.

    Each bottle of Natrol Melatonin Gummies contains 90 gummies, providing a 45-day supply when used as directed. Adults are advised to take two gummies 30 minutes before bedtime for optimal results. These gummies offer a drug-free option for sleep aid, helping to regulate the body’s natural sleep cycle and improving sleep quality. While effective for occasional sleep disruptions, users should consult with their doctor if taking medication or experiencing any medical conditions before use.

    Key Highlights:

    • 10 mg melatonin per serving
    • Strawberry-flavored, vegetarian, and non-GMO
    • Free from artificial flavors, synthetic dyes, and common allergens
    • Pectin-based formula for easier chewing
    • 90-count bottle for a 45-day supply

    Who it’s best for:

    • Adults struggling with occasional sleeplessness
    • Frequent travelers needing sleep support in unfamiliar environments
    • People looking for a non-habit-forming sleep aid
    • Individuals avoiding artificial ingredients and gelatin in supplements

    6. Alteril Natural Sleep Aid Soft Gel

    Alteril Natural Sleep Aid Soft Gel 60ct is designed for those who struggle with sleeplessness, providing a non-narcotic and non-habit-forming solution. This product combines several natural ingredients like L-Tryptophan, GABA, Valerian Root Extract, Chamomile Extract, and Melatonin. These components are known for promoting relaxation and improving sleep quality. The soft gel form is fast-acting, so it is convenient for those looking for immediate relief from sleeplessness.

    This product is easy to use and comes in a portable packaging ideal for travel. With no prescription required, Alteril is available for purchase online and ships with all the necessary accessories. A blend of ingredients designed to support falling asleep and staying asleep naturally.

    Key Highlights:

    • Fast-acting, non-narcotic formula
    • Contains natural ingredients like L-Tryptophan, Melatonin, and Valerian Root
    • Portable and easy-to-use soft gel capsules
    • Non-habit forming
    • Aims to improve both falling asleep and staying asleep

    Who it’s best for:

    • Individuals with occasional sleeplessness or mild insomnia
    • Travelers needing a non-habit-forming sleep aid
    • People sensitive to traditional prescription sleep medications
    • Those seeking a natural approach to better sleep

    7. Zarbee's Kids 1mg Melatonin Gummy

    Zarbee's Kids 1mg Melatonin Gummies offer a simple option for parents looking to support their child’s occasional sleeplessness. Each gummy contains 1 mg of melatonin, a naturally occurring hormone in the body that helps regulate sleep cycles. These gummies are designed for children aged 3 and up and come in a natural berry flavor. The product is drug-free, non-habit forming, and made with ingredients such as honey and pectin, with no artificial flavors, sweeteners, or gelatin.

    These melatonin gummies are gluten-free, alcohol-free, and recommended by pediatricians as a sleep aid for children. They work naturally with the body’s sleep rhythm and are intended for occasional use to help children settle down at bedtime. The convenient gummy form is easy for kids to take, and parents appreciate the peace of mind that comes with a non-habit-forming product for sleep support.

    Key Highlights:

    • 1 mg of melatonin per gummy
    • Drug-free and non-habit forming
    • Natural berry flavor, sweetened with honey
    • Free of artificial sweeteners, gelatin, and gluten
    • Pediatrician recommended

    Who it’s best for:

    • Children aged 3 and up with occasional sleep disruptions
    • Parents seeking a natural, non-habit-forming sleep aid for their kids
    • Families looking for a gluten-free, vegetarian-friendly product

    8. Hyland's Calms Forté® Tablets

    Hyland's Calms Forté® Tablets are formulated to support relaxation and calm during periods of sleeplessness or stress. They focus on easing stress, anxiety, and nervous irritability, using homeopathically-prepared ingredients. This over-the-counter sleep aid promotes a natural and gentle approach to sleep without the use of diphenhydramine or other synthetic ingredients. The tablets contain botanical ingredients like chamomile and hops, as well as minerals, to support a calming effect.

    Produced in the USA, Calms Forté® is free of allergens, artificial flavors, synthetic dyes, and parabens. The product is cruelty-free, with sustainably sourced ingredients when possible. It aims to offer a non-drowsy solution for those seeking to reduce tension before bedtime, particularly helpful during stressful travel situations where unfamiliar environments might cause restlessness.

    Key Highlights:

    • Homeopathically-prepared botanicals and minerals
    • Chamomilla (Chamomile) and Humulus Lupulus (Hops)
    • Free from allergens, artificial flavors, and synthetic dyes
    • Manufactured in the USA
    • Cruelty-free and paraben-free

    Who it’s best for:

    • Individuals who experience sleeplessness due to stress or anxiety
    • Travelers who find it difficult to sleep in new environments
    • People looking for a non-drowsy, natural sleep aid
    • Those who prefer cruelty-free and allergen-free products

    9. Aleve PM Sleep Aid Plus Pain Reliever

    This product combines naproxen sodium, a pain reliever, with diphenhydramine hydrochloride, a nighttime sleep aid, offering a solution for those who need both pain relief and a better night’s rest. The caplets are indicated for use by adults and children 12 years and older, and they work to help users fall asleep and stay asleep throughout the night. The 12-hour pain-relieving strength helps reduce discomfort from conditions such as muscle aches or headaches, which can interrupt sleep.

    Aleve PM is designed for people who struggle to sleep due to minor pain but don't require a prescription. The product provides a dual-action approach: managing pain and promoting restful sleep. It's available over-the-counter, with directions to take two caplets before bed for the best effect. As with any medication, users should follow the instructions carefully and consult a healthcare provider if they have any questions or concerns about the product’s use.

    Key Highlights:

    • Combines pain relief (naproxen sodium) with a sleep aid (diphenhydramine hydrochloride)
    • Provides up to 12 hours of pain relief
    • iIntended to support restful sleep, especially for minor discomforts.
    • Indicated for adults and children 12 years and older
    • Available in a 120-count package

    Who it’s best for:

    • People experiencing occasional sleeplessness due to minor aches and pains
    • Those looking for a combination of pain relief and sleep support
    • Adults and children aged 12 and older needing over-the-counter pain relief

    10. Amazon Basics Melatonin Gummies

    Amazon Basics offers melatonin gummies with a simple, strawberry-flavored formulation designed to support occasional sleep needs. Each gummy contains 5 mg of melatonin, an ingredient commonly used to aid in regulating sleep cycles, particularly useful for those who experience sleep disruptions while traveling. These gummies are vegan and gluten-free. The product comes in a bottle containing 120 gummies, providing a 60-serving supply based on the recommended dose of two gummies per serving.

    They are available as a straightforward, affordable option for individuals seeking a non-habit-forming supplement to improve sleep quality. The gummies are easy to consume and can be taken around 30 minutes before bedtime. As a product from the Amazon Basics line, they meet general standards for over-the-counter sleep aids, though they lack additional ingredients such as herbs or vitamins that some other sleep supplements may include.

    Key Highlights:

    • Contains 5 mg of melatonin per serving
    • Vegan and gluten-free formula
    • Comes in a strawberry flavor
    • 120 gummies per bottle, equating to 60 servings
    • Packaged in a recyclable bottle
    • Manufactured in the USA or Canada

    Who it’s best for:

    • Travelers who need help adjusting to different time zones
    • Individuals looking for a simple, melatonin-based sleep aid
    • Those preferring a vegan, gluten-free product
    • People who want a cost-effective solution for occasional sleep support

    11. Vitafusion SleepWell Gummies 

    Vitafusion SleepWell gummies are designed to help with sleep, particularly for those experiencing disruptions like jet lag. Each serving contains melatonin, a natural hormone that the body produces in response to darkness. By supplementing melatonin, Vitafusion SleepWell aims to restore the sleep-wake cycle that might be affected by travel or irregular sleep patterns. The gummies come in a white tea and peach flavor, providing a more enjoyable experience than traditional pills or capsules.

    The product is intended for adults and should be taken before bedtime to help promote sleep. It is sold as an over-the-counter dietary supplement and includes a clear recommendation to chew the gummies thoroughly before swallowing. This product is not meant to treat or cure any medical conditions, and its claims about helping with sleep are based on general information about melatonin's effects on the sleep cycle.

    Key Highlights:

    • Contains melatonin, a hormone that supports sleep
    • Formulated to help with jet lag and sleep disruptions
    • Each serving includes two gummies
    • White tea and peach flavor for a pleasant taste
    • Designed as a chewable gummy supplement

    Who it’s best for:

    • Travelers experiencing jet lag
    • Adults seeking help with sleep due to disruptions in routine
    • Individuals who prefer gummies over traditional pill forms
    • Those who want a melatonin-based sleep aid

    12. Sominex Nighttime Sleep-Aid

    Sominex Nighttime Sleep-Aid is designed for individuals looking for help with falling asleep quickly, especially in unfamiliar environments. Each tablet contains 25 mg of Diphenhydramine HCl, which is an antihistamine commonly used to promote drowsiness. It comes in tablet form, so it is convenient for use during travel. Though primarily advertised as a sleep aid, the product is non-habit forming and is intended for short-term use.

    This product is particularly suitable for those experiencing disrupted sleep patterns due to travel, jet lag, or sleeping in unfamiliar surroundings. While its formula is safe and effective for occasional use, it is important to consult with a healthcare professional if you plan to use it regularly or if you have pre-existing health conditions.

    Key Highlights:

    • Contains Diphenhydramine HCl 25 mg
    • Available in tablet form
    • Non-habit forming
    • Designed for short-term use
    • #203 in OTC Medicinal Sleep Aids

    Who it’s best for:

    • Travelers needing help adjusting to different time zones
    • People who struggle with falling asleep in new environments
    • Individuals looking for an over-the-counter solution for occasional sleeplessness
    • Adults who prefer non-habit forming sleep aids

    13. ZzzQuil Sleep Aid

    ZzzQuil is an over-the-counter sleep aid developed by Vicks, designed for those who occasionally struggle with falling asleep. It contains Diphenhydramine HCl, an ingredient that induces drowsiness by blocking histamine, a chemical responsible for keeping the brain awake. ZzzQuil is non-habit-forming, and it works within about 20 minutes after consumption, helping users fall asleep more easily and wake up feeling refreshed. Each dose consists of two liquid capsules, with 50mg of the active ingredient per dose. The product is widely available and comes in a 72-count package.

    This sleep aid is particularly suitable for short-term use when dealing with occasional sleeplessness, such as while traveling. With no added flavors, ZzzQuil focuses purely on providing sleep support. The product is designed to be taken before bedtime, offering a straightforward solution for those needing help to fall asleep, especially in unfamiliar environments like planes or hotels.

    Key Highlights:

    • Contains Diphenhydramine HCl 25 mg
    • Non-habit-forming formula
    • Works in about 20 minutes
    • Available in 72-count packaging
    • Designed for occasional sleeplessness
    • Manufactured by Vicks, a well-known healthcare brand

    Who it’s best for:

    • Travelers dealing with jet lag
    • Adults and kids experiencing occasional sleeplessness
    • Individuals who have trouble falling asleep quickly
    • Those looking for a non-habit-forming sleep aid

    14. Excedrin PM Sleep Aid with Headache Relief Caplets

    Excedrin PM Sleep Aid with Headache Relief Caplets is an over-the-counter product. This product combines two pain relievers, acetaminophen and aspirin, along with diphenhydramine citrate, a non-habit-forming sleep aid, to help users manage pain and sleeplessness at the same time. It is caffeine-free, so it is suitable for nighttime use without the risk of interfering with sleep patterns.

    The product is available in convenient caplet form and is intended for individuals aged 12 and older who experience headaches or body pain accompanied by sleeplessness. Its triple-action formula is particularly useful for those seeking both pain relief and the ability to sleep more comfortably, as it is a practical choice for anyone traveling or adjusting to new environments.

    Key Highlights:

    • Combines acetaminophen, aspirin, and diphenhydramine citrate
    • Caffeine-free formula designed for nighttime use
    • Provides relief from headaches and muscle pain
    • Available in caplet form for easy consumption
    • Suitable for individuals aged 12 and older

    Who it’s best for:

    • Individuals experiencing nighttime headaches and sleeplessness
    • People seeking a combination of pain relief and a sleep aid
    • Travelers dealing with body pain or discomfort in new environments
    • Adults 12 years and older looking for a non-habit-forming sleep aid

    15. Unisom SleepTabs, Nighttime Sleep-Aid 

    Unisom SleepTabs are an over-the-counter sleep aid designed to help individuals fall asleep faster and stay asleep throughout the night. The active ingredient, Doxylamine Succinate, is known for its effectiveness in reducing the time it takes to fall asleep by 33%, compared to a placebo. This product is non-habit forming and is recommended for occasional sleeplessness. It comes in tablet form and is suitable for adults and children over the age of 12. One tablet should be taken approximately 30 minutes before bedtime to assist with falling asleep.

    In addition to helping with sleep onset, Unisom SleepTabs are marketed as a safe solution that does not cause lingering grogginess the following morning when used as directed. It is available in different packaging sizes, including 48 tablets per bottle. Unisom offers a range of other sleep aid products, but this specific formulation targets those needing support in falling asleep and staying asleep through the night.

    Key Highlights:

    • Contains 25 mg of Doxylamine Succinate per tablet
    • Helps users fall asleep 33% faster than placebo in clinical studies
    • Non-habit forming, safe for occasional sleeplessness
    • Available in various package sizes, including 48 tablets per bottle
    • Recommended for adults and children over 12 years old

    Who it’s best for:

    • People experiencing occasional sleeplessness
    • Individuals looking for a non-habit-forming sleep aid
    • Adults and children over 12 who need help falling asleep faster
    • Travelers who have trouble adjusting to new sleep environments
    • Those seeking an OTC sleep aid without morning grogginess

    16. Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets

    Tylenol PM Extra Strength - each caplet contains 500 mg of acetaminophen for pain relief and 25 mg of diphenhydramine HCl to help induce sleep. It's designed to help users fall asleep and stay asleep while addressing pain from headaches, muscle aches, and other minor discomforts. The product is recommended for adults and children over 12 years old.

    This over-the-counter option is non-habit forming when used as directed, and it comes from a well-known brand in pain relief. The caplets are available in different sizes, including a 150-count option. It’s a simple solution for people who need both pain relief and sleep support in one product.

    Key Highlights:

    • Combines acetaminophen (500 mg) and diphenhydramine HCl (25 mg) in each caplet
    • Provides temporary relief from minor aches and pains
    • Non-habit forming when used as directed
    • Designed for adults and children 12 years and older
    • Available in multiple pack sizes, including a 150-count option

    Who it’s best for:

    • People experiencing minor pain and difficulty falling asleep
    • Travelers who may need help sleeping in new environments
    • Adults and children over 12 years who want a non-habit forming sleep aid
    • Those seeking a dual-purpose product for pain relief and sleep assistance

    Conclusion

    In conclusion, finding the right OTC sleep aid for travel can make a huge difference in how well you rest while on the move. Whether you're dealing with long flights, different time zones, or just the unfamiliarity of hotel rooms, having a reliable sleep aid can help you get the rest you need to stay refreshed and ready for your trip. The options we've covered provide different approaches to help you sleep better, from addressing minor aches and pains to simply calming your mind so you can drift off.

    However, it’s always important to choose a product that fits your specific needs. Consider factors like whether you need pain relief or just help falling asleep, and always check the instructions and possible side effects before taking any medication. With the right OTC sleep aid in your travel kit, you’ll be able to tackle any travel-related sleep challenges with ease. Safe travels and restful nights ahead!

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